Test of Dihidroisocoumarin Activity Against Murine Leukemia Cells P-388 From the Stem Bark Extract of Shorea Singkawang (Miq) .Miq

Yusnelti Yusnelti, Yunazar Manjang, Abdi Dharma, Jaswir Darwis

Abstract


Has succeeded in isoalsi elegat acid compounds from the stem bark of dichloromethane fraction  Shorea Singkawang (Miq) .Miq and identified as dihidroisocoumarin or bergenin, based on the data of UV spectroscopy, IR, GC-MS and 1 H NMR and 13 C NMR, and. This compound is a derivative elegat acid that was first discovered in this plant, bioassay cytotoxic activity using P-388 cells. With the value of IC50 = 25, 33 lm / mL.


Keywords


Shorea Singkawang (Miq) .Miq; elagat acid, dihidroisocoumarin; Murin leukemia cells P-388; IC 50

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DOI: http://dx.doi.org/10.18517/ijaseit.4.2.373

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Published by INSIGHT - Indonesian Society for Knowledge and Human Development