Paper Strip Based on Nanoemulsion of Curcumin as Boric Acid Detection

Anting Wulandari, Titi Candra Sunarti, Farah Fahma, Erliza Noor, Toshiharu Enomae


Boric acid is a toxic contaminant chemical that is found not only in food but also in the environment, especially the water environment so that its existence needs to be detected. In this work, we design the paper strip using nanoemulsion curcumin for boric acid detection. Curcumin is a bioactive compound that is able to provide a color change response to boron. However, curcumin is not stable to certain environmental conditions, so it needs to be encapsulated. Since it has a low solubility so that the proper encapsulation technique is nanoemulsion. This study investigates nanoemulsion curcumin paper strips' performance as a colorimteric biosensor for the detection of boric acid. The results showed that nanoemulsion curcumin reagent (CURNnsr) as a boric acid detection had a smooth spherical shape with a size of 25.70 nm. Interaction between created curcumin paper strips and boric acid led to a color change from yellow to red. Curcumin paper strip was selective towards sole boric acid after being reacted with various chemicals such as Pb2+, Zn2+ , Fe2+, Mg2+, NaCl, sodium nitrite, monosodium glutamate, sodium benzoate, and formalin with a concentration of 10000 ppm, respectively. The detection limit (LOD) for curcumin paper strips was 105.56 ppm in the range 200-700 ppm of boric acid. This research results are pledging to develop disposable biosensors that are sensitive, selective, and stable, low cost, easy to use and detect quickly.


Biosensor; boric acid; curcumin; nanoemulsion; paper strip.

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